MODELING OF GAS-TRANSPORT FUNCTION OF ERYTHROCYTES IN HEMOGLOBIN SORPTION IMMOBILIZATION

Colloid-disperse systems based on haemoglobin sorption immobilization in reticular polyelectrolytes are proposed and investigated. The effic iency of oxygen transport of these systems is much higher than that of native haemoglobin and is comparable with the efficacy of gas transpo rt of erythrocytes. This is believed to be due to highly selective sor ption immobilization of haemoglobin in microdisperse forms of permeabl e carboxylic reticular polyelectrolytes. Microparticles exhibit high l ocal concentration of haemoglobin, the protein mass being by one order of magnitude higher than that of the polymer carrier.