The fast response (FR) is an early reduction in the amplitude of the f
MR signal occurring shortly after the onset of stimulation. Owing to i
ts potential advantages in terms of temporal and spatial resolution, i
t may be of considerable significance in functional experiments, A mod
el for the mechanism of the FR was developed which accounts for the fM
RS finding that the amplitude of the dip decreases with increasing ech
o time, Two computer simulations that confirmed the predictions of the
model and showed that it is possible to select optimal echo times for
the detection of the FR were performed.