PURPOSE: To report a case of marginal keratitis resulting from topical dorz
olamide hypersensitivity.
METHOD: Case report.
RESULTS: A 68 year old woman presented with bilateral marginal keratitis 2
weeks after commencing bilateral topical dorzolamide. One week after discon
tinuation of topical dorzolamide, the patient was asymptomatic with complet
e resolution of corneal infiltrates.
CONCLUSIONS: Topical dorzolamide may cause a hypersensitivity reaction in t
he form of marginal keratitis. Discontinuation of the offending medication
should result in complete resolution. (C) 2000 by Elsevier Science Inc. All
rights reserved.