Marginal keratitis: An uncommon form of topical dorzolamide allergy

PURPOSE: To report a case of marginal keratitis resulting from topical dorz olamide hypersensitivity. METHOD: Case report. RESULTS: A 68 year old woman presented with bilateral marginal keratitis 2 weeks after commencing bilateral topical dorzolamide. One week after discon tinuation of topical dorzolamide, the patient was asymptomatic with complet e resolution of corneal infiltrates. CONCLUSIONS: Topical dorzolamide may cause a hypersensitivity reaction in t he form of marginal keratitis. Discontinuation of the offending medication should result in complete resolution. (C) 2000 by Elsevier Science Inc. All rights reserved.