Sandifer's syndrome is a rare manifestation of gastroesophageal reflux (GER
) in children, occurring in association with abnormal movements of the head
, neck, and upper part of the trunk. Out of 65 children with Sandifer's syn
drome described in literature, only 2 were breast-fed. We report on a 15-da
y-old breast-fed girl affected by Sandifer's syndrome. Pathological GER was
diagnosed with 24 h pH esophageal monitoring. In our patient, all the symp
toms of Sandifer's syndrome disappeared when she was cow's milk formula-fed
. The role of food allergy to dietary proteins ingested by a lactating moth
er is discussed.