Anaphylaxis or significant hypersensitivity reaction is one of the most cat
astrophic potential complications of chemotherapy. There is a 2-5% risk of
hypersensitivity with paclitaxel, a commonly used chemotherapeutic agent fo
r various cancers. Three patients, who developed hypersensitivity to paclit
axel infusion, received docetaxel without allergic reactions. Docetaxel may
therefore be an alternative treatment for patients with paclitaxel hyperse
nsitivity. [(C) 2000 Lippincott Williams & Wilkins].