In vitro pharmacodynamic characteristics of nystatin including time-kill and postantifungal effect

Authors
Gunderson, SM Hoffman, H Ernst, EJ Pfaller, MA Klepser, ME
Citation
Sm. Gunderson et al., In vitro pharmacodynamic characteristics of nystatin including time-kill and postantifungal effect, ANTIM AG CH, 44(10), 2000, pp. 2887-2890
Citations number
12
Categorie Soggetti
Microbiology
Journal title
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
ISSN journal
00664804 → ACNP
Volume
44
Issue
10
Year of publication
2000
Pages
2887 - 2890
Database
ISI
SICI code
0066-4804(200010)44:10<2887:IVPCON>2.0.ZU;2-I
Abstract
Four Candida albicans isolates and six non-albicans Candida isolates were e valuated by time-kill methods to characterize the relationship between nyst atin concentrations, the rate and extent of fungicidal activity, and the po stantifungal effect (PAFE). Against Candida species, nystatin exhibits conc entration-dependent fungicidal activity and a pronounced PAFE.