This paper reviews applications of therapeutic electrical stimulation (ES)
specific to wound healing and pressure sore prevention. The application of
ES for wound healing has been found to increase the rate of healing by more
than 50%. Furthermore, the total number of wounds heated is also increased
. However, optimal delivery techniques for ES therapy have not been establi
shed to date. A study of stimulation current effects on wound healing in a
pig model has shown that direct current (DC) stimulation is most effective
in wound area reduction and alternating current (AC) stimulation for wound
volume reduction at current densities of 127 mu A/cm(2) and 1,125 mu A/cm(2
), respectively. Preliminary studies have been carried out at two research
centers to assess the role of ES in pressure sore prevention. Surface stimu
lation studies have shown that ES can produce positive shortterm changes in
tissue health variables such as regional blood flow and pressure distribut
ion. The use of an implanted stimulation system consisting of intramuscular
electrodes with percutaneous leads has been found to produce additional lo
ng-term changes. Specifically, gluteal muscle thickness increased by 50% wi
th regular long-term ES application concurrent with a 20% decrease in regio
nal interface pressures and increased tissue oxygen levels. These findings
indicate that an implantable ES system map have great potential for pressur
e sore prevention, particularly For individuals who lack sensation or who a
re physically unable to perform regular independent pressure relief.