Retrospective analysis of 30 patients with pathological fracture out of 336
patients with primary malignant bone tumors should demonstrate the influen
ce a pathologic fracture and the form of surgical therapy have on the survi
val rate. In 25 out of 30 patients a fracture led to diagnosis of the disea
se. Pathological fractures occurred cumulatively by malignant fibrous histi
ocytoma of the bone and in tumor stages IIb and III. Surgery was performed
on 26 out of 30 patients (12 ablative therapies, 14 reconstructive therapie
s). The mortality risk for patients with pathological fractures was more th
an double the risk for patients without pathological fractures (P = 0.0062)
, When performed correctly, reconstructive therapy does not influence the s
urvival rate.