Our own series of tumors of the upper cervical spine was analyzed retrospec
tively. The standard treatment strategies were reevaluated. A total of nine
patients (mean age 61 years, metastasis 4, plasmocytoma 3, chordoma 1, his
tiocytosis 1) were treated between 1/92 and 2/99. A total of 12 operations
were carried out. One-step procedures (6): Three extraoral, one transoral,
one dorsal and in one case combined dorsal and extraoral tumor removal were
performed. Three dorsal occipitocervical or atlantoaxial stabilizations. o
ne ventral plating and two combined ventral plating plus dorsal three-point
fixations, and four vertebral body replacements were carried out. Two-step
procedures (3): three extraoral tumor removals with ventral plating plus d
orsal three-point fixation, in combination with vertebral body replacement
in two cases. The neurological status and the quality of life (Karnofsky pe
rformance status, pain levels) were analyzed preoperatively and at the foll
ow-up outpatient examinations (mean follow-up: 18 months). Flexion-extensio
n radiographs were performed at the follow-up. There was no operative morta
lity. The transient morbidity was 11 %. The operative intervention improved
the quality of life in all patients. Three patients died within 27 months
of operation. Tumor resection at the upper cervical spine using individuall
y modified surgical strategies over an approach corresponding to the tumor
location, stabilization and vertebral body replacement increases significan
tly the time of survival and quality of life with an acceptable surgical ri
sk for complications.