BACKGROUND: Calcium channel blockers are effective agents for the mana
gement of chronic hypertension and are being used with increasing freq
uency. If their safety and efficacy during pregnancy can be documented
, women can be counseled to continue their antihypertensive agent duri
ng pregnancy. To our knowledge, the use of felodipine, a calcium chann
el blocker of the dihydropyridine group, during pregnancy has not been
described. CASES: We report three cases of felodipine use in pregnanc
y by women with chronic hypertension. CONCLUSION: In women with severe
hypertension (diastolic blood pressure >100 mm Hg) who require pharma
cologic treatment of it during pregnancy, felodipine appears to be an
acceptable option.