Combined factor V and VIII deficiency in Indian population

The clinical and haematological heterogeneity in cases of the rare combined factor V and VIII deficiency has not been reported so far from India. Nine such cases belonging to five unrelated families have been analysed in the present study for the various haematological and clinical parameters. A ver y mild clinical presentation is seen in all these cases. The clinical manif estations, however, do not correlate with the plasma levels of these factor s.