Probing biopolymers with the atomic force microscope: A review

Citation
Hg. Hansma et al., Probing biopolymers with the atomic force microscope: A review, J BIOM SC P, 11(7), 2000, pp. 675-683
Citations number
51
Categorie Soggetti
Multidisciplinary
Journal title
JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
ISSN journal
09205063 → ACNP
Volume
11
Issue
7
Year of publication
2000
Pages
675 - 683
Database
ISI
SICI code
0920-5063(2000)11:7<675:PBWTAF>2.0.ZU;2-J
Abstract
This short review presents an overview of atomic force microscopy (AFM) of biopolymers and specific examples of some of the biopolymers that have been analyzed by AFM. These specific examples include extracellular polymeric s ubstances on the surfaces of bacterial biofilms; condensed DNA, DNA constru cts, and DNA-protein interactions. In addition, two examples are presented for AFM analyses of proteins: laminin flexing its arms in solution and neur ofilaments entropically brushing away the space around themselves.