Single-crystal aluminas are being considered for use in the manufacture of
prosthetic heart valves. To characterize such materials for biomedical appl
ication, subcritical crack growth by stress corrosion (static fatigue) and
by cyclic fatigue has been examined in sapphire along (1 (1) over bar 00) p
lanes in 24 degrees C humid air and 37 degrees C Ringer's solution (the lat
ter as a simulated physiological environment). The relationships between cr
ack-propagation rates and the linear-elastic stress intensity have been det
ermined for the first time in sapphire for both modes of subcritical cracki
ng. It was found that growth rates were significantly faster at a given str
ess intensity in the Ringer's solution compared to the humid air environmen
t. Mechanistically, a true cyclic fatigue effect was not found in sapphire
as experimentally measured cyclic fatigue-crack growth rates could be close
ly predicted simply by integrating the static fatigue-crack growth data ove
r the cyclic lending cycle. (C) 2000 John Wiley & Sons, Inc.