The 1990s have been characterized by an increasing understanding of the rol
e of psychologic disturbance and social stress and particularly the signifi
cance of a history of physical or sexual abuse as concomitants to chronic g
astrointestinal disorders. Irritable bowel syndrome, functional abdominal p
ain, esophageal motility disturbances, and other functional and motility di
sorders of the gastrointestinal tract have been increasingly viewed as biop
sychosocial illnesses with behavioral as well as somatic dimensions. The ap
plication of the behavioral sciences to the study of gastrointestinal dysfu
nction has generated tremendous advances in understanding these complex dis
orders. Studies of psychiatric comorbidity have subsequently led to advance
ments in treatment using psychopharmacological and psychotherapeutic modali
ties. The ability to appreciate the significance of psychosocial variables
in chronic gastrointestinal disorders has implications not only for improvi
ng the treatment of patients with these common disorders, but also for impr
oving the care of patients with a wide variety of chronic medical illnesses
.