The functional architecture of human auditory cortex is still poorly unders
tood compared with that of visual cortex, yet anatomical and electrophysiol
ogical studies in non-human primates suggest that the auditory cortex also
might be functionally specialized. in a model of parallel and hierarchical
organization. In particular, spectral changes such as the formant transitio
ns of speech, or spectral motion (SM) by analogy with visual motion, could
be processed in specialized cortical regions. In this study, positron emiss
ion tomography (PEI) was used to identify which auditory cortical region ar
e involved in SM analysis. We found that a bilateral secondary auditory cor
tical region, located in the caudal-lateral belt of auditory cortex, was mo
re sensitive to auditory stimuli containing spectral changes than to matche
d stimuli with a stationary spectral profile. This result suggests that ana
logies between sensory systems could prove useful in the research into the
functional organization of the auditory cortex. NeuroReport 11:2969-2972 (C
) 2000 Lippincott Williams & Wilkins.