We present a child with neurofibromatosis type I (NF-I) who underwent excis
ion of a large upper lid neurofibroma using a CO2-laser. Plexiform neurofib
romas are notorious for their bleeding tendency and the inability to achiev
e complete surgical excision. The CO2-laser is an adjunct to achieving bett
er hemostasis and delineation of the tissue in the absence of natural tissu
e planes caused by the tumor's diffuse mode of growth. Using the CO2-laser
achieves better cosmesis, while reducing operation time and limiting compli
cations.