Hs. Bridge et al., Analgesic efficacy of ketorolac 0.5% ophthalmic solution (Accular) in paediatric strabismus surgery, PAEDIATR AN, 10(5), 2000, pp. 521-526
This prospective double-blind study was designed to assess the analgesic ef
ficacy of ketorolac 0.5% ophthalmic solution compared with placebo in 30 he
althy children undergoing extraocular muscle recession for correction of st
rabismus. After paracetamol 20 mg.kg(-1) preoperatively, a standard anaesth
etic was given. There were no significant differences in Children's Hospita
l of Eastern Ontario Pain Scale (CHEOPS) and faces pain scale (FPS) scores,
requirement for supplementary analgesia or in postoperative vomiting betwe
en the two groups over the following 24 h. This study did not demonstrate i
mproved postoperative analgesia when topical ketorolac eye drops were given
in addition to paracetamol. This observed lack of efficacy may reflect dif
ficulties in the use of CHEOPS and FPS in this age group with this pain mod
el.