Analgesic efficacy of ketorolac 0.5% ophthalmic solution (Accular) in paediatric strabismus surgery

Citation
Hs. Bridge et al., Analgesic efficacy of ketorolac 0.5% ophthalmic solution (Accular) in paediatric strabismus surgery, PAEDIATR AN, 10(5), 2000, pp. 521-526
Citations number
25
Categorie Soggetti
Aneshtesia & Intensive Care
Journal title
PAEDIATRIC ANAESTHESIA
ISSN journal
11555645 → ACNP
Volume
10
Issue
5
Year of publication
2000
Pages
521 - 526
Database
ISI
SICI code
1155-5645(200009)10:5<521:AEOK0O>2.0.ZU;2-5
Abstract
This prospective double-blind study was designed to assess the analgesic ef ficacy of ketorolac 0.5% ophthalmic solution compared with placebo in 30 he althy children undergoing extraocular muscle recession for correction of st rabismus. After paracetamol 20 mg.kg(-1) preoperatively, a standard anaesth etic was given. There were no significant differences in Children's Hospita l of Eastern Ontario Pain Scale (CHEOPS) and faces pain scale (FPS) scores, requirement for supplementary analgesia or in postoperative vomiting betwe en the two groups over the following 24 h. This study did not demonstrate i mproved postoperative analgesia when topical ketorolac eye drops were given in addition to paracetamol. This observed lack of efficacy may reflect dif ficulties in the use of CHEOPS and FPS in this age group with this pain mod el.