Antinociceptive activity of a hydroalcoholic extract obtained from aerial parts of Sebastiania schottiana (Euphorbiaceae)

Authors
Luzzi, R Scheidt, C Roos, JF Cechinel, V Santos, ARS Calixto, JB Yunes, RA Niero, R
Citation
R. Luzzi et al., Antinociceptive activity of a hydroalcoholic extract obtained from aerial parts of Sebastiania schottiana (Euphorbiaceae), PHARMAZIE, 55(9), 2000, pp. 681-683
Citations number
16
Categorie Soggetti
Pharmacology & Toxicology
Journal title
PHARMAZIE
ISSN journal
00317144 → ACNP
Volume
55
Issue
9
Year of publication
2000
Pages
681 - 683
Database
ISI
SICI code
0031-7144(200009)55:9<681:AAOAHE>2.0.ZU;2-1
Abstract
This study analyzed the antinociceptive effects of a hydroalcoholic extract obtained from the aerial parts of Sebastiania schottiana, a Brazilian medi cinal plant used to treat various painful diseases. For this purpose, the w rithing test, capsaicin and formalin induced-pain in mice were used. The re sults showed that the hydroalcoholic extract exhibited considerable antinoc iception in all the models studied, being more potent than aspirin.