Three novel diterpenoids have been isolated from the roots of Croton macros
tachys. The structure and stereochemistry of the compounds have been unambi
guously settled as neoclerodan-5,10-en-19,6 beta;20,12-diolide, 3 alpha,19-
dihydroxytrachylobane, and 3 alpha,18,19-trihydroxytrachylobane from detail
ed spectroscopic evidence. (C) 2000 Elsevier Science Ltd. All rights reserv
ed.