Dermatomyositis associated with the presence of parvovirus B19 DNA in muscle

Authors
Chevrel, G Calvet, A Belin, V Miossec, P
Citation
G. Chevrel et al., Dermatomyositis associated with the presence of parvovirus B19 DNA in muscle, RHEUMATOLOG, 39(9), 2000, pp. 1037-1039
Citations number
16
Categorie Soggetti
Rheumatology
Journal title
RHEUMATOLOGY
ISSN journal
14620324 → ACNP
Volume
39
Issue
9
Year of publication
2000
Pages
1037 - 1039
Database
ISI
SICI code
1462-0324(200009)39:9<1037:DAWTPO>2.0.ZU;2-X
Abstract
We report a case of dermatomyositis associated with molecular evidence of p arvovirus B19 DNA in two muscle biopsies collected 5 months apart. IgG- but not IgM-specific antibodies were detected in serum. None of four serum sam ples was positive for parvovirus B19 DNA. The two biopsies contained B19 VP I sequences and the second one was also positive for NS1. This is the first report of viral parvovirus B19 DNA in muscle of a patient with dermatomyos itis. Latent muscle infection may contribute to the clinical picture.