A facile synthesis of benzo[4,5]imidazo[2,1-b]pyrimido[5,4-f][1,3,4]thiadiazepines

Authors
Brukstus, A Melamedaite, D Tumkevicius, S
Citation
A. Brukstus et al., A facile synthesis of benzo[4,5]imidazo[2,1-b]pyrimido[5,4-f][1,3,4]thiadiazepines, SYN COMMUN, 30(20), 2000, pp. 3719-3730
Citations number
16
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNTHETIC COMMUNICATIONS
ISSN journal
00397911 → ACNP
Volume
30
Issue
20
Year of publication
2000
Pages
3719 - 3730
Database
ISI
SICI code
0039-7911(2000)30:20<3719:AFSOB>2.0.ZU;2-D
Abstract
Benzo[4,5]imidazo[2,1-b]pyrimido[5,4-f][1,3,4]thiadiazepines representing a new heterocyclic system were prepared by cyclocondensation reaction of 1-a minobenzimidazol-2-thione with 6-chloropyrimidine-5-carbaldehydes. 4-Dimeth ylamino derivative of this tetraheterocyclic system possessed anti-HIV acti vity.