Chiral ferrocenyl amino alcohols as analogues of norephedrine catalysts for enantioselective addition of diethylzinc to benzaldehyde

Authors
Bastin, S Brocard, J Pelinski, L
Citation
S. Bastin et al., Chiral ferrocenyl amino alcohols as analogues of norephedrine catalysts for enantioselective addition of diethylzinc to benzaldehyde, TETRAHEDR L, 41(38), 2000, pp. 7303-7307
Citations number
25
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
38
Year of publication
2000
Pages
7303 - 7307
Database
ISI
SICI code
0040-4039(20000916)41:38<7303:CFAAAA>2.0.ZU;2-#
Abstract
Optically active ferrocenyl amino alcohols have been prepared from commerci ally available L-alaninol and L-leucinol. They have been used in catalytic amounts as chiral ligands in the addition of diethylzinc to benzaldehyde. 1 -Phenylpropanol has thus been obtained in up to 95% enantiomeric excess. (C ) 2000 Elsevier Science Ltd. All rights reserved.