Citation
Bl. Maroto et al., A new highly efficient synthetic route to enantiopure 10-bromocamphor, TETRAHEDR-A, 11(15), 2000, pp. 3059-3062
Citations number
23
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166
→ ACNP
Volume
11
Issue
15
Year of publication
2000
Pages
3059 - 3062
Database
ISI
SICI code
0957-4166(20000811)11:15<3059:ANHESR>2.0.ZU;2-D
Abstract
A new enantiospecific synthetic route to the interesting chiral synthetic i
ntermediate 10-bromocamphor starting from readily available camphor is desc
ribed. The procedure takes place straightforwardly in only three synthetic
steps with high overall yield. Mechanistically, two interesting enantiospec
ific Wagner-Meerwein rearrangements involving 2-norbornyl carbocations take
place during the process. (C) 2000 Elsevier Science Ltd. All rights reserv
ed.