A concise synthesis of (S)-(-)-3-(2-carboxy-4-pyrrolyl)-alanine

Authors
Adamczyk, M Johnson, DD Reddy, RE
Citation
M. Adamczyk et al., A concise synthesis of (S)-(-)-3-(2-carboxy-4-pyrrolyl)-alanine, TETRAHEDR-A, 11(15), 2000, pp. 3063-3068
Citations number
11
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
11
Issue
15
Year of publication
2000
Pages
3063 - 3068
Database
ISI
SICI code
0957-4166(20000811)11:15<3063:ACSO(>2.0.ZU;2-S
Abstract
A convergent synthesis of (S)-(-)-3-(2-carboxy-4-pyrrolyl)-alanine (CPA) 1, a non-proteinogenic amino acid is described starting from a commercially a vailable dimethyl L-aspartate 2 in good overall yield. (C) 2000 Elsevier Sc ience Ltd. All rights reserved.