Conserved noncoding sequences are reliable guides to regulatory elements

Authors
Hardison, RC
Citation
Rc. Hardison, Conserved noncoding sequences are reliable guides to regulatory elements, TRENDS GEN, 16(9), 2000, pp. 369-372
Citations number
22
Categorie Soggetti
Molecular Biology & Genetics
Journal title
TRENDS IN GENETICS
ISSN journal
01689525 → ACNP
Volume
16
Issue
9
Year of publication
2000
Pages
369 - 372
Database
ISI
SICI code
0168-9525(200009)16:9<369:CNSARG>2.0.ZU;2-V
Abstract
A 'working draft' of the human genome sequence is now available. Comparison s with the sequences of mouse and other species will be a powerful approach to identifying functional segments of the noncoding regions, such as gene regulatory elements. However, the choice of a species for most effective co mparison differs among various loci.