A pilot study has ascribed an important role in gallbladder motility and em
ptying to the perimenopausal period. To assess the effect of this period on
gallbladder emptying and cholelithogenesis, 25 women in the perimenopausal
period without gallbladder disease were submitted to cholangiography and t
wo ultrasound exams, The time for gallbladder emptying and the presence of
cholelithiasis were assessed, All patients presented a delay in gallbladder
emptying with no relationship to the pre- or postmenopausal period. This f
inding was not related to lithogenesis. Gallbladder emptying time is longer
during the perimenopausal period.