Solid-phase synthesis of novel achiral hydantoin- and isoxazoline-substituted dispirocyclobutanoids

Authors
Park, KH Kurth, MJ
Citation
Kh. Park et Mj. Kurth, Solid-phase synthesis of novel achiral hydantoin- and isoxazoline-substituted dispirocyclobutanoids, CHEM COMMUN, (19), 2000, pp. 1835-1836
Citations number
23
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
19
Year of publication
2000
Pages
1835 - 1836
Database
ISI
SICI code
1359-7345(2000):19<1835:SSONAH>2.0.ZU;2-T
Abstract
A synthesis of novel achiral hydantoin- and isoxazoline-substituted dispiro cyclobutanoids from solid-phase synthesis has been achieved. The facial and selective Boc-NH-mediated hydrogen-bond delivery of the nitrile oxide affo rded 6 as the major compound.