Development of a family of beta-amino alcohol ligands with two stereocenters for highly efficient enantioselective trimethylsilylcyanation of aldehydes

Authors
You, JS Gau, HM Choi, MCK
Citation
Js. You et al., Development of a family of beta-amino alcohol ligands with two stereocenters for highly efficient enantioselective trimethylsilylcyanation of aldehydes, CHEM COMMUN, (19), 2000, pp. 1963-1964
Citations number
21
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
19
Year of publication
2000
Pages
1963 - 1964
Database
ISI
SICI code
1359-7345(2000):19<1963:DOAFOB>2.0.ZU;2-G
Abstract
The asymmetric addition of Me3SiCN to aldehydes catalyzed by titanium(iv) c omplexes of N-sulfonylated derivatives of beta-amino alcohols gave excellen t ee's up to 96% ee.