In this paper, which is written at an elementary and pedagogical level, we
discuss general aspects of (single) instantons in SU(N) Yang-Mills theory,
and then specialize to the case of N =4 supersymmetry and the large-N limit
. We show how to determine the measure of collective coordinates and comput
e instanton corrections to certain correlation functions. We then relate th
is to D-instantons in type IIB supergravity. By taking the D-instantons to
live in an AdS(5) x S-5 background, we perform explicit: checks of the AdS-
CFT correspondence.