THE HELICOBACTER REVOLUTION

Citation
Al. Blum et al., THE HELICOBACTER REVOLUTION, Leber, Magen, Darm, 27(3), 1997, pp. 170
Citations number
57
Categorie Soggetti
Gastroenterology & Hepatology
Journal title
ISSN journal
03008622
Volume
27
Issue
3
Year of publication
1997
Database
ISI
SICI code
0300-8622(1997)27:3<170:THR>2.0.ZU;2-A
Abstract
H. pylori defies the physicochemical defence of gastric mucosa mechani sms using his mobility, his adapted acid metabolism and his adherence to the gastric epithelium, The immune-biological defence of the host i s unable to eliminate the infection Helicobacter infection always lead s to gastritis. Progression to more serious disorders depends on the H elicobacter strain, on host factors and on the environment. Helicobact er plays an essential role in the pathogenesis of gastric and duodenal ulcers and of MALT-lymphoma. H. pylori contributes to the development of gastric carcinoma. Its role in functional dyspepsia is controversi al; its role in extra-gastroduodenal diseases such as myocardial infar ction is highly controversial.