Diabetes insipidus in neurobrucellosis

Brucellosis is an infection due to Brucella species and is characterized by acute febrile illness, chilly sensations, sweats, weakness, generalized ma laise, body aches and headache. The involvement of the nervous system is ra re. A few cases have been reported with symptoms and sign of optic neuritis , meningoencephalitis, meningomyelitis and cranial nerve palsy. We report a case with culture proven neurobrucellosis who presented with diabetes insi pidus along with systemic signs. Neuroimaging revealed multiple lesions in brain parenchyma, including the suprasellar region. Both diabetes and supra sellar lesions improved markedly with specific antibiotic therapy. (C) 2000 Elsevier Science B.V. All rights reserved.