A CONVENIENT SYNTHESIS OF MONOGENATED AND POLYHALOGENATED BENZOCYCLANONES

Authors
CORNELIUS LAM COMBS DW
Citation
Lam. Cornelius et Dw. Combs, A CONVENIENT SYNTHESIS OF MONOGENATED AND POLYHALOGENATED BENZOCYCLANONES, Synthetic communications, 24(19), 1994, pp. 2777-2788
Citations number
30
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthetic communications → ACNP
ISSN journal
00397911
Volume
24
Issue
19
Year of publication
1994
Pages
2777 - 2788
Database
ISI
SICI code
0039-7911(1994)24:19<2777:ACSOMA>2.0.ZU;2-6
Abstract
Benzocyclanones were mono- or dihalogenated on the aromatic ring with elemental halogen or N-halosuccinimide without solvent in an aluminum chloride slurry in good yield. This process is the most direct method for the synthesis of 5- or 7-halo, or 5,7-dihalotetralones and can be extended to indan-1 -ones and benzocycloheptan-1 -ones as well as to t rihalogenated and to mixed halogenated products.