Citation
Sc. Kaul et al., Structurally and functionally distinct mouse hsp70 family members Mot-1 and Mot-2 proteins are encoded by two alleles, DNA RES, 7(3), 2000, pp. 229-231
Citations number
8
Categorie Soggetti
Molecular Biology & Genetics
Journal title
DNA RESEARCH
ISSN journal
13402838
→ ACNP
Volume
7
Issue
3
Year of publication
2000
Pages
229 - 231
Database
ISI
SICI code
1340-2838(20000630)7:3<229:SAFDMH>2.0.ZU;2-M
Abstract
The mouse mortalin proteins Mot-1 and Mot-2 differ by two amino acids in th
eir carboxy-terminus. These proteins are differentially localized in the ce
ll cytoplasm and have contrasting biological activities. The genetic relati
onship between Mot-1 and Mot-2 was deciphered by mouse family analyses. Mot
-2 and Mot-2 segregated in F-1 and F-2 progeny, providing direct evidence t
hat the two proteins are encoded by two alleles.