EFFECTS OF IMMUNOMODULATORS ON POSTIRRADIATION RECOVERY IN THE THYMUS

The effect of immunomodulatory agents on reparation processes in the t hymus was studied in mice injured by a single sublethal or lethal dose of ionizing radiation ranging between 6.5-9.5 Gy. Reparation of thymu s weight was not influenced by pretreatment with immunomodulators. Fur thermore, the morphological picture did not exhibit appreciable differ ences between non-protected and protected groups, except for greater p roliferation of fibroblasts and macrophages in protected animals.