THE EFFECT OF TRIIODOTHYRONINE ON CELL OXIDATIVE CAPACITY IN REGENERATING RAT-LIVER

The recovery of total DNA content and recovery of total cytochrome c o xidase activity in the rat liver after partial hepatectomy is accelera ted by triiodothyronine applied in three doses, two before and one imm ediately after liver resection. Triiodothyronine-treated animals alrea dy have higher cytochrome c oxidase activity before resection. The rec overy of the tissue oxidative capacity after partial hepatectomy is mo re rapid in triiodothyronine-treated animals. These data indicate that hormonal activation of the liver regeneration process is involved.