Dialkyl 1-alkynylphosphonates: A range of promising reagents

Authors
Iorga, B Eymery, F Carmichael, D Savignac, P
Citation
B. Iorga et al., Dialkyl 1-alkynylphosphonates: A range of promising reagents, EUR J ORG C, (18), 2000, pp. 3103-3115
Citations number
149
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
ISSN journal
1434193X → ACNP
Issue
18
Year of publication
2000
Pages
3103 - 3115
Database
ISI
SICI code
1434-193X(200009):18<3103:D1AROP>2.0.ZU;2-4
Abstract
This review covers the preparations of 1-alkynylphosphonates by Michaelis-A rbuzov and Michaelis-Becker reactions, by nucleophilic substitutions at pho sphorus (SNPV), and by elimination from 1-alkenylphosphonates. The reactivi ty and versatility of 1-alkynylphosphonates have made them valuable precurs ors for other phosphonates, and particularly for the synthesis of heterocyc les by [2+2], [3+2], and [4+2] cycloaddition reactions.