Unprecedented poisoning terrorism by use of sarin took place in Japan in 19
94 and 1995. On July 25, 1998, a curry poisoning incident in Wakayama occur
red resulting in the death of four people and injury of 63 people. Since th
en, more than 30 imitative poisoning cases have been reported by mass commu
nication within 1 year. In this brief review, we present some details of a
series of poisoning cases and measures taken by the Japanese Government and
non-government groups. In addition some research projects on analytical to
xicology being conducted in our laboratories are also introduced; gas chrom
atography (OC) with cryogenic oven trapping for volatile organic compounds,
and GC/surface ionization organic mass spectrometry For tertiary amino com
pounds are described especially as new techniques for biological samples. (
C) 2000 Elsevier Science Ireland Ltd. All rights reserved.