Objective: To assess the degree of sexual mixing in a sexually transmi
tted disease clinic population stratified by country of birth. Design:
Prospective linked HIV serosurvey incorporating demographic and sexua
l risk data gathered by a doctor-administered questionnaire. Setting:
The Department of Genitourinary Medicine at St Thomas' Hospital, Londo
n, UK. Subjects: Fifteen thousand eight hundred and seventy-eight hete
rosexuals who attended between April 1992 and February 1995. Main outc
ome measure: The degree of assortative (like-with-like) mixing, after
stratification of the population by country of birth, of index patient
s, their parents and their sexual partners. Results: Sexual mixing in
this population of sexually transmitted disease clinic attenders is hi
ghly assortative when the CoB of parents (family origin) of index pati
ents is taken into account. Conclusions: Our findings help to explain
the low spread of heterosexual HIV infection in the UK to date, and ma
y help future projections and health targeting of those at risk. This
model can be applied to other mixed populations.