A follow-up study of balloon angioplasty and de-novo stenting in Takayasu arteritis

Percutaneous balloon angioplasty (PTBA) is a universally accepted mode of t herapy for stenotic coronary and peripheral arterial lesions. To establish the role of PTBA and stent placement in patients with Takayasu's arteritis (TA), these procedures were performed in 20 patients with TA. All patients received steroids, aspirin and ticlodipine (for stent placement) prior to p rocedure. Angioplasty was carried in patients with symptomatic stenotic ves sel of more than 70% of normal diameter or a peak systolic gradient of more than 50 mm across stenotic aortic lesion. Stenting was performed for ostia l lesion, long segment lesion or incomplete relief of stenosis and dissecti on following angioplasty. Carotid angioplasty and stenting was performed in five: patients, aortic angioplasty in nine patients, aortic angioplasty an d stenting in four patients, renal angioplasty in three patients, renal ang ioplasty and stenting in two patients and subclavian angioplasty in two pat ients, subclavian, angioplasty and stenting in three patients and coronary angioplasty and stent placement in one patient. The procedure was successfu l in all but one patient. On following up, two patients with carotid stent placement had restenosis. A saccular aneurysm developed at the lower end of stent in one patient with aortic stent placement. The PTBA with or without stent placement is a safe and effective method for relief of stenotic lesi on in patients with TA. (C) 2000 Elsevier Science Ireland Ltd. All rights r eserved.