In this article we describe a real-time automated reminder system that has
been developed to change Family Physicians' (FP) test ordering behavior. Th
e system focuses on the appropriateness of test requests. We aim at using t
he system as a substitute for written feedback by human experts. The remind
er system consists of a knowledge base, an order entry system and modules t
o provide passive and active support in the form of reminders to FPs. The s
ystem generates critical comments about the rationality of the test request
s at the moment the FP orders a test that is not in line with national or r
egional guidelines. For the first validation of the knowledge base we compa
red the comments of a human expert to the comments of the reminder system o
n three random samples of test requests. The overall agreement in the subse
quent validation rounds was 46, 60 and 69%. The corrections made in the kno
wledge base after each validation round resulted in a reminder system with
149 reminders concerning Various medical problems. Due to the corrections i
n the knowledge base the reminder system reacts better over the subsequent
validation rounds. (C) 2000 Elsevier Science Ireland Ltd. All rights reserv
ed.