Tardive extrapyramidal symptoms (EPS) induced by neuroleptic treatment, and
particularly EPS which persist after withdrawal of the drugs, are clinical
ly serious problems. We describe a patient with four types of tardive and p
ersistent EPS such as dystonia, dyskinesia, choreatic movement and myoclonu
s, induced by haloperidol. These EPS weve remarkably inhibited by 3 mg/day
risperidone. This is the first published case demonstrating simultaneous de
velopment of these four types of tardive EPS induced by a neuroleptic and t
hen reduced by low-dose risperidone treatment.