An echocardiographic description of the Sulzer Carbomedics Synergy ST (Labcor) porcine valve in the aortic position

Citation
J. Chambers et al., An echocardiographic description of the Sulzer Carbomedics Synergy ST (Labcor) porcine valve in the aortic position, J HEART V D, 9(5), 2000, pp. 661-666
Citations number
17
Categorie Soggetti
Cardiovascular & Respiratory Systems
Journal title
JOURNAL OF HEART VALVE DISEASE
ISSN journal
09668519 → ACNP
Volume
9
Issue
5
Year of publication
2000
Pages
661 - 666
Database
ISI
SICI code
0966-8519(200009)9:5<661:AEDOTS>2.0.ZU;2-C
Abstract
Background and nim of the study: The Synergy ST (previously Labcor) valve i s constructed from three separate porcine aortic cusps mounted on a scallop ed, flexible, acetal copolymer stent. To date, no hemodynamic data describi ng this valve have been published. The aim of this study was to describe th e echocardiographic findings in a population of unselected patients. Methods: One investigator, who was blinded to valve size, studied 84 patien ts (31 females, 53 males; mean age 58 years; range: 19-83 years) at four ce nters in Brazil. The valves were studied at a mean of 31 months after impla ntation (range: 1-116 months). Mean gradient was calculated using the long modified Bernoulli equation, effective orifice area (EOA) using the classic al from of the continuity equation, and resistance as mean gradient/flow. Results:There were no significant differences in peak transaortic velocity and mean gradient between valves of different annulus size. However, EOA wa s directly related (p = 0.0075) and resistance indirectly related to valve size (p = 0.021, ANOVA). Trivial or mild regurgitation was seen in 31 patie nts (37%), moderate in three (4%) and severe in two (2%). The regurgitation was solely paraprosthetic in five patients, solely through the valve in 23 , and both in seven. Regurgitation through the valve usually occurred adjac ent to the commissures. Conclusion: The Synergy ST porcine valve has hemodynamics of forward flow s imilar to that of other stented porcine valves.