An improved procedure for the synthesis of 4,4-disubstituted-3-oxo-1,2,5-thiadiazolidine 1,1-dioxides

Authors
Xiao, ZJ Timberlake, JW
Citation
Zj. Xiao et Jw. Timberlake, An improved procedure for the synthesis of 4,4-disubstituted-3-oxo-1,2,5-thiadiazolidine 1,1-dioxides, J HETERO CH, 37(4), 2000, pp. 773-777
Citations number
23
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
JOURNAL OF HETEROCYCLIC CHEMISTRY
ISSN journal
0022152X → ACNP
Volume
37
Issue
4
Year of publication
2000
Pages
773 - 777
Database
ISI
SICI code
0022-152X(200007/08)37:4<773:AIPFTS>2.0.ZU;2-F
Abstract
An improved synthesis for the preparation of 3-oxo-1,2,5-thiadiazolidine 1, l-dioxides has been developed. This facile two-step procedure from cc-amino acid esters and chlorosulfonyl isocyanate results in excellent yields of p roducts.