Bioactive carotanes from Trichoderma virens

Authors
Macias, FA Varela, RM Simonet, AM Cutler, HG Cutler, SJ Eden, MA Hill, RA
Citation
Fa. Macias et al., Bioactive carotanes from Trichoderma virens, J NAT PROD, 63(9), 2000, pp. 1197-1200
Citations number
29
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
01633864 → ACNP
Volume
63
Issue
9
Year of publication
2000
Pages
1197 - 1200
Database
ISI
SICI code
0163-3864(200009)63:9<1197:BCFTV>2.0.ZU;2-Y
Abstract
Four new metabolites with carotane skeletons, trichocaranes A (1), B (2), C (3), and D (4), were isolated from Trichoderma virens and their structures established by the interpretation of NMR and mass spectroscopic data. The trichocaranes significantly inhibited the growth of etiolated wheat coleopt iles: 40% at 10(-4) M with 1 and 2 and 86% at 10(-3) M with 3.