Streptazones A, B-1, B-2, C, and D: New piperidine alkaloids from streptomycetes

Authors
Puder, C Krastel, P Zeeck, A
Citation
C. Puder et al., Streptazones A, B-1, B-2, C, and D: New piperidine alkaloids from streptomycetes, J NAT PROD, 63(9), 2000, pp. 1258-1260
Citations number
20
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
01633864 → ACNP
Volume
63
Issue
9
Year of publication
2000
Pages
1258 - 1260
Database
ISI
SICI code
0163-3864(200009)63:9<1258:SABBCA>2.0.ZU;2-Q
Abstract
Five new piperidine alkaloids (1-5), named streptazones A, B-1, B-2, C, and D, were isolated from Streptomyces strains FORM5 and Al. Their structures were established on the basis of detailed MS and NMR analysis. Streptazone A (1) exhibited significant cytotoxic activity against selected human tumor cell lines.