Absolute configuration and antiprotozoal activity of minquartynoic acid

Citation
Hb. Rasmussen et al., Absolute configuration and antiprotozoal activity of minquartynoic acid, J NAT PROD, 63(9), 2000, pp. 1295-1296
Citations number
10
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
01633864 → ACNP
Volume
63
Issue
9
Year of publication
2000
Pages
1295 - 1296
Database
ISI
SICI code
0163-3864(200009)63:9<1295:ACAAAO>2.0.ZU;2-U
Abstract
Minquartynoic acid (1) was isolated as an antimalarial and antileishmanial constituent of the Peruvian tree Minquartia guianensis and its absolute con figuration at C-17 established to be (+)-S through conversion to the known (+)-(S)-17-hydroxystearic acid (2) and confirmed using Mosher's method.