Treatment of recalcitrant ulcers in pyoderma gangrenosum with mycophenolate mofetil and autologous keratinocyte transplantation on a hyaluronic acid matrix

Authors
Wollina, U Karamfilov, T
Citation
U. Wollina et T. Karamfilov, Treatment of recalcitrant ulcers in pyoderma gangrenosum with mycophenolate mofetil and autologous keratinocyte transplantation on a hyaluronic acid matrix, J EUR A D V, 14(3), 2000, pp. 187-190
Citations number
21
Categorie Soggetti
Dermatology
Journal title
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
ISSN journal
09269959 → ACNP
Volume
14
Issue
3
Year of publication
2000
Pages
187 - 190
Database
ISI
SICI code
0926-9959(200005)14:3<187:TORUIP>2.0.ZU;2-W
Abstract
Pyoderma gangrenosum sometimes takes a recalcitrant course that is unrespon sive to standard immunosuppression with corticosteroids and/or cyclosporin A. In these cases improvement of painful ulcerations is a therapeutic chall enge. We report a 17-year-old boy with severe pyoderma gangrenosum treated successfully with mycophenolate mofetil and autologous keratinocyte transpl antation using an esterified hyluronic acid delivery system.