The ability of six probiotic bacteria to bind a common food carcinogen, afl
atoxin B-1, was assessed. The studied strains included Lactobacillus strain
s and one Bifidobacterium strain. The strains were incubated in vitro with
alfatoxin B1 and the toxin residue in the supernatant was measured using hi
gh-performance Liquid chromatography. The aflatoxin-binding capacity of the
strains was found to range from 5.8 to 31.3%. The results further support
the observation that a number of probiotic bacteria are able to bind specif
ic dietary contaminants. Although the extent of binding varies depending on
the bacterial strain used, the data may explain some of the antimutagenic
and anticarcinogenic effects of probiotic micro-organisms. (C) 2000 Society
of Chemical Industry.