Bactericidal activity of catechin-copper (II) complexes against Staphylococcus aureus compared with Escherichia coli

Authors
Hoshino, N Kimura, T Hayakawa, F Yamaji, A Ando, T
Citation
N. Hoshino et al., Bactericidal activity of catechin-copper (II) complexes against Staphylococcus aureus compared with Escherichia coli, LETT APPL M, 31(3), 2000, pp. 213-217
Citations number
13
Categorie Soggetti
Biotecnology & Applied Microbiology",Microbiology
Journal title
LETTERS IN APPLIED MICROBIOLOGY
ISSN journal
02668254 → ACNP
Volume
31
Issue
3
Year of publication
2000
Pages
213 - 217
Database
ISI
SICI code
0266-8254(200009)31:3<213:BAOC(C>2.0.ZU;2-Q
Abstract
The bactericidal activity of catechin-copper (II) complexes against Staphyl ococcus aureus compared with Escherichia coli was investigated in relation to the generation of hydrogen peroxide and the binding of Cu(II) ion onto t he bacteria. The bactericidal activity of catechin-Cu(II) complexes against Staph. aureus (Gram-positive) was much lower than that against E. coli (Gr am-negative), suggesting that the binding of copper ions to the surface of bacterial cells plays an important role in the bactericidal activity of cat echin-Cu(II) complexes.