Much of the very extensive literature describing the (bio)chemistry and bio
logy of bacterial lipopolysaccharides (LPS, endotoxin) has dealt with the p
roperties of these molecules as potent triggers of host responses. This bri
ef review will focus on what has been learned recently about mechanisms by
which the host can dispose of LPS and counter its often excessive stimulato
ry effects. (C) 2000 Editions scientifiques et medicales Elsevier SAS.